Using Diphenylphosphoryl Azide (DPPA) for the facile synthesis of biodegradable antiseptic random copolypeptides

Using Diphenylphosphoryl Azide (DPPA) for the facile synthesis of biodegradable antiseptic random copolypeptides

We have developed a facile method for the large-scale synthesis of random copolypeptides composed of multiple (i.e. cationic, hydrophobic, and hydrophilic) amino acids and have optimized their relative ratios for broad-spectrum antibacterial effect. The copolypeptides obtained have measured composit...

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Bibliographic Details
Main Authors: Pu, Yuji, Du, Yu, Khin, Mya Mya, Ravikumar, Vikashini, Rice, Scott A., Duan, Hongwei, Chan-Park, Mary B.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2018
Subjects:
Antibacterial Peptides
Broad-spectrum Antibacterial Activity
Online Access:https://hdl.handle.net/10356/80350
http://hdl.handle.net/10220/45009
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/80350
http://hdl.handle.net/10220/45009

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