NMR characterization and membrane interactions of the loop region of kindlin-3 F1 subdomain

• المؤلفون الرئيسيون: Chua, Geok-Lin, Tan, Suet-Mien, Bhattacharjya, Surajit
• مؤلفون آخرون: Mofrad, Mohammad R. K.
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: DRNTU::Science::Biological sciences; Membrane Interactions; F1 Loop
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/80464; http://hdl.handle.net/10220/46562
• المؤسسة: Nanyang Technological University

Kindlins-1,2 and 3 are FERM domain-containing cytosolic proteins involved in the activation and regulation of integrin-mediated cell adhesion. Apart from binding to integrin β cytosolic tails, kindlins and the well characterized integrin-activator talin bind membrane phospholipids. The ubiquitin-lik...