NMR characterization and membrane interactions of the loop region of kindlin-3 F1 subdomain

• Main Authors: Chua, Geok-Lin, Tan, Suet-Mien, Bhattacharjya, Surajit
• Other Authors: Mofrad, Mohammad R. K.
• Format: Article
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Biological sciences; Membrane Interactions; F1 Loop
• Online Access: https://hdl.handle.net/10356/80464; http://hdl.handle.net/10220/46562
• Institution: Nanyang Technological University

Kindlins-1,2 and 3 are FERM domain-containing cytosolic proteins involved in the activation and regulation of integrin-mediated cell adhesion. Apart from binding to integrin β cytosolic tails, kindlins and the well characterized integrin-activator talin bind membrane phospholipids. The ubiquitin-lik...