Transformation of Cortex-wide Emergent Properties during Motor Learning

• Main Authors: Makino, Hiroshi, Ren, Chi, Liu, Haixin, Kim, An Na, Kondapaneni, Neehar, Liu, Xin, Kuzum, Duygu, Komiyama, Takaki
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Motor learning; Wide-field calcium imaging
• Online Access: https://hdl.handle.net/10356/80528; http://hdl.handle.net/10220/43426
• Institution: Nanyang Technological University

Learning involves a transformation of brain-wide operation dynamics. However, our understanding of learning-related changes in macroscopic dynamics is limited. Here, we monitored cortex-wide activity of the mouse brain using wide-field calcium imaging while the mouse learned a motor task over weeks....