Organic additives stabilize RNA aptamer binding of malachite green

• Main Authors: Zhou, Yubin, Chi, Hong, Wu, Yuanyuan, Marks, Robert S., Steele, Terry W. J.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2017
• Subjects: Malachite green aptamer; Malachite green
• Online Access: https://hdl.handle.net/10356/80594; http://hdl.handle.net/10220/42176
• Institution: Nanyang Technological University

Aptamer-ligand binding has been utilized for biological applications due to its specific binding and synthetic nature. However, the applications will be limited if the binding or the ligand is unstable. Malachite green aptamer (MGA) and its labile ligand malachite green (MG) were found to have incre...