Pronounced peptide selectivity for melanoma through tryptophan end-tagging

• Main Authors: Duong, Dinh Thuy, Singh, Shalini, Bagheri, Mojtaba, Verma, Navin Kumar, Schmidtchen, Artur, Malmsten, Martin
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2016
• Online Access: https://hdl.handle.net/10356/80656; http://hdl.handle.net/10220/40585
• Institution: Nanyang Technological University

Effects of oligotryptophan end-tagging on the uptake of arginine-rich peptides into melanoma cells was investigated under various conditions and compared to that into non-malignant keratinocytes, fibroblasts, biophysical studies on peptide binding to, and destabilization of, model lipid membranes pr...