The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD

• Main Authors: Leung, Janice M., Tiew, Pei Yee, Mac Aogáin, Micheál, Budden, Kurtis F., Yong, Valerie Fei Lee, Thomas, Sangeeta Susan, Pethe, Kevin, Hansbro, Philip M., Chotirmall, Sanjay Haresh
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Acute exacerbations of chronic obstructive pulmo-nary disease; Chronic obstructive pulmonary disease
• Online Access: https://hdl.handle.net/10356/80784; http://hdl.handle.net/10220/42256
• Institution: Nanyang Technological University

COPD is a major global concern, increasingly so in the context of ageing populations. The role of infections in disease pathogenesis and progression is known to be important, yet the mechanisms involved remain to be fully elucidated. While COPD pathogens such as Haemophilus influenzae, Moraxella cat...