Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells

Background: Pluripotent embryonic stem cells (ESCs) have the unique ability to differentiate into every cell type and to self-renew. These characteristics correlate with a distinct nuclear architecture, epigenetic signatures enriched for active chromatin marks and hyperdynamic binding of structural...

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Main Authors: Mattout, Anna, Aaronson, Yair, Sailaja, Badi Sri, Raghu Ram, Edupuganti V., Harikumar, Arigela, Mallm, Jan-Philipp, Sim, Kae Hwan, Nissim-Rafinia, Malka, Supper, Emmanuelle, Singh, Prim B., Sze, Siu Kwan, Gasser, Susan M., Rippe, Karsten, Meshorer, Eran
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Online Access:https://hdl.handle.net/10356/81001
http://hdl.handle.net/10220/39029
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Institution: Nanyang Technological University
Language: English