Synthesis and characterization of multifunctional hybrid-polymeric nanoparticles for drug delivery and multimodal imaging of cancer

• Main Authors: Tng, Danny Jian Hang, Song, Peiyi, Lin, Guimiao, Soehartono, Alana Mauluidy, Yang, Guang, Yang, Chengbin, Yin, Feng, Tan, Cher Heng, Yong, Ken-Tye
• Other Authors: School of Electrical and Electronic Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: Nanoparticles; Individualized; Cancer; Multicellular tumor spheroids; Hybrid-polymeric
• Online Access: https://hdl.handle.net/10356/81042; http://hdl.handle.net/10220/39077
• Institution: Nanyang Technological University

In this study, multifunctional hybrid-polymeric nanoparticles were prepared for the treatment of cultured multicellular tumor spheroids (MCTS) of the PANC-1 and MIA PaCa-2 pancreatic carcinoma cell lines. To synthesize the hybrid-polymeric nanoparticles, the poly lactic-co-glycolic acid core of the...