Functional VEGFA knockdown with artificial 3′-tailed mirtrons defined by 5′ splice site and branch point

Functional VEGFA knockdown with artificial 3′-tailed mirtrons defined by 5′ splice site and branch point

Mirtrons are introns that form pre-miRNA hairpins after splicing to produce RNA interference (RNAi) effectors distinct from Drosha-dependent intronic miRNAs, and will be especially useful for co-delivery of coding genes and RNAi. A specific family of mirtrons – 3′-tailed mirtrons – has hairpins prec...

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Bibliographic Details
Main Authors: Kock, Kian Hong, Kong, Kiat Whye, Hoon, Shawn, Seow, Yiqi
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2015
Subjects:
Biological Sciences
Online Access:https://hdl.handle.net/10356/81115
http://hdl.handle.net/10220/39104
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/81115
http://hdl.handle.net/10220/39104

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