Identification of DNA Motif with Mutation

• Main Author: Shu, Jian-Jun
• Other Authors: School of Mechanical and Aerospace Engineering
• Format: Article
• Language: English
• Published: 2015
• Subjects: DNA coding; Scoring matrix; Sequence analysis
• Online Access: https://hdl.handle.net/10356/81178; http://hdl.handle.net/10220/39172
• Institution: Nanyang Technological University

The conventional way of identifying possible motif sequences in a DNA strand is to use representative scalar weight matrix for searching good match substring alignments. However, this approach, solely based on match alignment information, is susceptible to a high number of ambiguous sites or false p...