Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

• Main Authors: Ju, Y.S, Alexandrov, L.B, Gerstung, M
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: DNA; mitochondrial DNA; animal; classification; data mining; DNA base composition; DNA replication; genetics; high throughput sequencing; human; mitochondrial genome; mitochondrion; molecular evolution; mutation; neoplasm; pathology; single nucleotide polymorphism; Animals; Base Composition; Data Mining; DNA Replication; DNA, Mitochondrial; DNA, Neoplasm; Evolution, Molecular; Genome, Mitochondrial; High-Throughput Nucleotide Sequencing; Humans; Mitochondria; Mutation; Neoplasms; Polymorphism, Single Nucleotide
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/182033
• Institution: National University of Singapore

10.7554/eLife.02935