Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

• Main Authors: Ju, Y.S, Tubio, J.M.C, Mifsud, W
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Cold Spring Harbor Laboratory Press 2020
• Subjects: mitochondrial DNA; Article; bacterial artificial chromosome; cancer cell; cell nucleus transplantation; chromosome 10; chromosome 11; controlled study; DNA end joining repair; DNA replication; DNA replication origin; double stranded DNA break; fluorescence in situ hybridization; fusion gene; gene expression; gene rearrangement; gene sequence; human; human cell; human genome; interphase; mitochondrial DNA replication; mitochondrial genome; primary tumor; priority journal; somatic cell; transformed cell; transposon; amino acid sequence; cell nucleus; chromosome; copy number variation; DNA sequence; genetics; HeLa cell line; mitochondrion; molecular genetics; neoplasm; reproducibility; tumor cell line; Amino Acid Sequence; Cell Line, Tumor; Cell Nucleus; Chromosomes; DNA Copy Number Variations; DNA End-Joining Repair; DNA Replication; DNA, Mitochondrial; Genome, Human; Genome, Mitochondrial; HeLa Cells; Humans; In Situ Hybridization, Fluorescence; Mitochondria; Molecular Sequence Data; Neoplasms; Reproducibility of Results; Sequence Analysis, DNA
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179660
• Institution: National University of Singapore

10.1101/gr.190470.115