Metabolic reprogramming of tumor-infiltrating myeloid cells conveys protection against pancreatic ductal adenocarcinoma

Myriad mechanisms of immune evasion contribute to therapeutic resistance of pancreatic cancer and poor survival. While it is well established that tumor cells exhibit the Warburg effect for energy production, the contribution of myeloid cell metabolism to disease progression is unknown. In this stud...

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Bibliographic Details
Main Author: Sieow, Je Lin
Other Authors: Wong Siew Cheng
Format: Theses and Dissertations
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/81283
http://hdl.handle.net/10220/47516
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Institution: Nanyang Technological University
Language: English