Copper-catalyzed aerobic radical C-C bond cleavage of N-H ketimines

• Main Authors: Tnay, Ya Lin, Ang, Gim Yean, Chiba, Shunsuke
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: copper; ketimines; molecular oxygen; radical; C-C bond cleavage
• Online Access: https://hdl.handle.net/10356/81491; http://hdl.handle.net/10220/40822
• Institution: Nanyang Technological University

We report herein studies on copper-catalyzed aerobic radical C-C bond cleavage of N-H ketimines. Treatment of N-H ketimines having an alpha-sp3 hybridized carbon under Cu-catalyzed aerobic reaction conditions resulted in a radical fragmentation with C-C bond cleavage to give the corresponding carbon...