Studying Protein–DNA Complexes Using Gold Nanoparticles by Exploiting Particle Aggregation, Refractive Index Change, and Fluorescence Quenching and Enhancement Principles

• Main Authors: Sutarlie, Laura, Aung, Khin Moh Moh, Lim, Michelle Gek Liang, Lukman, Steven, Cheung, Edwin, Su, Xiaodi
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: Protein–DNA complexes; Gold nanoparticles
• Online Access: https://hdl.handle.net/10356/81780; http://hdl.handle.net/10220/40976
• Institution: Nanyang Technological University

Gold nanoparticles (AuNPs) have a unique optical phenomena termed localized surface plasmon resonance that is determined by particle shape, size, interparticle distance (or aggregation status), and local refractive index. AuNPs can also modulate fluorescence emission of proximal fluorophores under t...