Trimerization of enones under air enabled by NHC/NaOtBu via a SET radical pathway

• Main Authors: Zhang, Yuexia, Wu, Xingxing, Hao, Lin, Wong, Zeng Rong, Lauw, Sherman Jun Liang, Yang, Song, Webster, Richard David, Chi, Yonggui Robin
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Trimerization; Radical intermediates
• Online Access: https://hdl.handle.net/10356/81973; http://hdl.handle.net/10220/42449
• Institution: Nanyang Technological University

An unusual trimerization of enone via a formal [2 + 2 + 2] process is disclosed. The reaction is initiated by a radical process enabled by NaOtBu and N-heterocyclic carbene (NHC). Molecular oxygen (air) is involved in key steps of the radical intermediate formation and carbon–carbon bond cleavage in...