The fetal mouse metatarsal bone explant as a model of angiogenesis

• Main Authors: Song, Weihua, Fhu, Chee Wai, Ang, Koon Hwee, Liu, Cheng Hao, Johari, Nurul Azizah Binte, Lio, Daniel, Abraham, Sabu, Hong, Wanjin, Moss, Stephen E, Greenwood, John, Wang, Xiaomeng
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2016
• Subjects: Cell and Tissue Culture; Functional Analysis
• Online Access: https://hdl.handle.net/10356/82099; http://hdl.handle.net/10220/41107
• Institution: Nanyang Technological University

The mouse fetal metatarsal provides a unique tool for studying angiogenesis. In comparison with other commonly used in vitro or ex vivo angiogenesis assays, vessel outgrowth from mouse fetal metatarsals is more representative of sprouting angiogensis in vivo. It allows the analysis of blood vessel g...