A topological approach for protein classification

• Main Authors: Cang, Zixuan, Mu, Lin, Wu, Kedi, Opron, Kristopher, Xia, Kelin, Wei, Guo-Wei
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: persistent homology; machine learning
• Online Access: https://hdl.handle.net/10356/82112; http://hdl.handle.net/10220/41120; http://www.degruyter.com/view/j/mlbmb.2015.3.issue-1/mlbmb-2015-0009/mlbmb-2015-0009.xml?format=INT
• Institution: Nanyang Technological University

Protein function and dynamics are closely related to its sequence and structure.However, prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology. Protein classification, which is typically done through measuring the similarity...