Design and synthesis of beta-peptides as antimicrobial agents or adjuvants

• Main Author: Si, Zhangyong
• Other Authors: Chan Bee Eng, Mary
• Format: Thesis-Doctor of Philosophy
• Language: English
• Published: Nanyang Technological University 2019
• Subjects: Engineering::Chemical engineering::Biochemical engineering
• Online Access: https://hdl.handle.net/10356/82226; http://hdl.handle.net/10220/50470
• Institution: Nanyang Technological University

Most antibiotics were discovered five to seven decades ago, and they underpin many modern medical interventions such as surgery, cancer therapy, etc. However, no new class of antibiotics against Gram-negative bacteria has been discovered over the last 50 years. Meanwhile, bacteria mutate and develop...