Hollow microparticles as a superior delivery system over solid microparticles for the encapsulation of peptides

• Main Authors: Loo, Joachim Say Chye, Gautam, Archana, Kharel, Sharad, Dickescheid, Andreas
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2019
• Subjects: PLGA; Biodegradable; DRNTU::Engineering::Materials
• Online Access: https://hdl.handle.net/10356/82262; http://hdl.handle.net/10220/48032
• Institution: Nanyang Technological University

Purpose Peptides are gaining significant interests as therapeutic agents due to their high targeting specificity and potency. However, their low bioavailability and short half-lives limit their massive potential as therapeutics. The use of dense, solid particles of biodegradable polymer as a uni...