Expanded identification and characterization of mammalian circular RNAs

• Main Authors: Guo, Junjie U., Agarwal, Vikram, Guo, Huili, Bartel, David P.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2016
• Subjects: Medicine
• Online Access: https://hdl.handle.net/10356/82403; http://hdl.handle.net/10220/40041
• Institution: Nanyang Technological University

Background: The recent reports of two circular RNAs (circRNAs) with strong potential to act as microRNA (miRNA) sponges suggest that circRNAs might play important roles in regulating gene expression. However, the global properties of circRNAs are not well understood.Results: We developed a computati...