Argonaute identity defines the length of mature mammalian microRNAs

MicroRNAs (miRNAs) are 19- to 25-nt-long non-coding RNAs that regulate gene expression by base-pairing with target mRNAs and reducing their stability or translational efficiency. Mammalian miRNAs function in association with four closely related Argonaute proteins, AGO1–4. All four proteins contain...

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Bibliographic Details
Main Authors: Makeyev, Eugene V., Juvvuna, Prasanna Kumar, Khandelia, Piyush, Lee, Li Ming
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/96954
http://hdl.handle.net/10220/10002
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Institution: Nanyang Technological University
Language: English