Argonaute identity defines the length of mature mammalian microRNAs

• المؤلفون الرئيسيون: Makeyev, Eugene V., Juvvuna, Prasanna Kumar, Khandelia, Piyush, Lee, Li Ming
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2013
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/96954; http://hdl.handle.net/10220/10002

MicroRNAs (miRNAs) are 19- to 25-nt-long non-coding RNAs that regulate gene expression by base-pairing with target mRNAs and reducing their stability or translational efficiency. Mammalian miRNAs function in association with four closely related Argonaute proteins, AGO1–4. All four proteins contain...