Not just an adhesion molecule : LFA-1 contact tunes the T lymphocyte program

The αLβ2 integrin LFA-1 is known to play a key role in T lymphocyte migration, which is necessary to mount a local immune response, and is also the main driver of autoimmune diseases. This migration-triggering signaling process in T cells is tightly regulated to permit an immune response that is app...

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Bibliographic Details
Main Authors: Verma, Navin Kumar, Kelleher, Dermot
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/82500
http://hdl.handle.net/10220/49072
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Institution: Nanyang Technological University
Language: English