Not just an adhesion molecule : LFA-1 contact tunes the T lymphocyte program
The αLβ2 integrin LFA-1 is known to play a key role in T lymphocyte migration, which is necessary to mount a local immune response, and is also the main driver of autoimmune diseases. This migration-triggering signaling process in T cells is tightly regulated to permit an immune response that is app...
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Main Authors: | , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
2019
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/82500 http://hdl.handle.net/10220/49072 |
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Institution: | Nanyang Technological University |
Language: | English |