The Closed State of the Thin Filament Is Not Occupied in Fully Activated Skeletal Muscle

Muscle contraction is powered by actin-myosin interaction controlled by Ca2+ via the regulatory proteins troponin (Tn) and tropomyosin (Tpm), which are associated with actin filaments. Tpm forms coiled-coil dimers, which assemble into a helical strand that runs along the whole ∼1 μm length of a thin...

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Bibliographic Details
Main Authors: Bershitsky, Sergey Y., Koubassova, Natalia A., Kopylova, Galina V., Ferenczi, Michael Alan, Narayanan, Theyencheri, Tsaturyan, Andrey K.
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10356/82599
http://hdl.handle.net/10220/42317
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Institution: Nanyang Technological University
Language: English