Nickel-catalyzed asymmetric transfer hydrogenation of conjugated olefins

• Main Authors: Guo, Siyu, Yang, Peng, Zhou, Jianrong Steve
• Other Authors: School of Physical and Mathematical Sciences
• Format: Article
• Language: English
• Published: 2016
• Subjects: Chemistry and Biological Chemistry
• Online Access: https://hdl.handle.net/10356/82663; http://hdl.handle.net/10220/40239
• Institution: Nanyang Technological University

Asymmetric transfer hydrogenation of electron-deficient olefins is realized with nickel catalysts supported by strongly σ-donating bisphosphines. Deuterium labeling experiments point to a reaction sequence of formate decarboxylation, asymmetric hydride insertion and non-stereoselective protonation o...