Polarizing the Neuron through Sustained Co-expression of Alternatively Spliced Isoforms

• Main Authors: Yap, Karen, Xiao, Yixin, Friedman, Brad A., Je, H. Shawn, Makeyev, Eugene V.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2017
• 主題: Eukaryotic proteomes; Cdc42 in neurons
• 在線閱讀: https://hdl.handle.net/10356/83051; http://hdl.handle.net/10220/42371
• 機構: Nanyang Technological University

Alternative splicing (AS) is an important source of proteome diversity in eukaryotes. However, how this affects protein repertoires at a single-cell level remains an open question. Here, we show that many 30-terminal exons are persistently co-expressed with their alternatives in mammalian neuro...