Block copolymer nanoparticles remove biofilms of drug-resistant gram-positive bacteria by nanoscale bacterial debridement

• Main Authors: Li, Jianghua, Zhang, Kaixi, Ruan, Lin, Chin, Seow Fong, Wickramasinghe, Nirmani, Liu, Hanbin, Ravikumar, Vikashini, Ren, Jinghua, Duan, Hongwei, Yang, Liang, Chan-Park, Mary Bee Eng
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Article
• Language: English
• Published: 2018
• Subjects: Antibiofilm; Biocompatibility
• Online Access: https://hdl.handle.net/10356/83167; http://hdl.handle.net/10220/45046
• Institution: Nanyang Technological University

Biofilms and the rapid evolution of multidrug resistance complicate the treatment of bacterial infections. Antibiofilm agents such as metallic–inorganic nanoparticles or peptides act by exerting antibacterial effects and, hence, do not combat biofilms of antibiotics-resistant strains. In this Letter...