A semiconducting polymer nano-prodrug for hypoxia-activated synergetic photodynamic cancer therapy

• المؤلفون الرئيسيون: Cui, Dong, Huang, Jiaguo, Zhen, Xu, Li, Jingchao, Jiang, Yuyan, Pu, Kanyi
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: Photodynamic Therapy; Cancer Therapy; Engineering::Chemical engineering
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83296; http://hdl.handle.net/10220/50100

Photodynamic therapy (PDT) holds great promise for cancer therapy; however, its efficacy is often compromised by tumor hypoxia. Herein, we report the synthesis of a semiconducting polymer nanoprodrug (SPNpd) that not only efficiently generates singlet oxygen (1O2) under NIR photoirradiation but also...