Hemodynamic shear stress stimulates migration and extravasation of tumor cells by elevating cellular oxidative level

• المؤلفون الرئيسيون: Ma, Shijun, Fu, Afu, Chiew, Geraldine Giap Ying, Luo, Kathy Qian
• مؤلفون آخرون: School of Chemical and Biomedical Engineering
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Circulating tumor cells; Shear stress
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83325; http://hdl.handle.net/10220/42525

Cancer cells are shed into the blood stream and are exposed to hemodynamic shear stress during metastasis. It has been shown that shear stress can destroy circulating tumor cells (CTCs) both in vitro and in vivo. However, it remains unclear whether shear stress can modulate the properties and functi...