The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain

• Main Authors: Guo, Huichen, Huang, Mei, Yuan, Quan, Wei, Yanquan, Gao, Yuan, Mao, Lejiao, Gu, Lingjun, Tan, Yong Wah, Zhong, Yanxin, Liu, Dingxiang, Sun, Shiqi
• Other Authors: Cao, Yongchang
• Format: Article
• Language: English
• Published: 2017
• Subjects: Lipids; Membrane proteins
• Online Access: https://hdl.handle.net/10356/83486; http://hdl.handle.net/10220/42639
• Institution: Nanyang Technological University

Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular membrane during the entry of IBV into host cells is still unknown. In this study, we biochemically fractionated I...