A novel toolbox to investigate tissue spatial organization applied to the study of the islets of Langerhans

• Main Authors: Tran Thi Nhu, Hoa, Arrojo E. Drigo, Rafael, Berggren, Per-Olof, Boudier, Thomas
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2017
• Subjects: Image processing; Diabetes
• Online Access: https://hdl.handle.net/10356/83497; http://hdl.handle.net/10220/42644
• Institution: Nanyang Technological University

Thanks to the development of new 3D Imaging techniques, volumetric data of thick samples, especially tissues, are commonly available. Several algorithms were proposed to analyze cells or nuclei in tissues, however these tools are limited to two dimensions. Within any given tissue, cells are not like...