Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes

Insulin resistance and β-cell failure are the major defects in type 2 diabetes mellitus. However, the molecular mechanisms linking these two defects remain unknown. Elevated levels of apolipoprotein CIII (apoCIII) are associated not only with insulin resistance but also with cardiovascular disorders...

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Main Authors: Leibiger, Ingo B., Leibiger, Barbara, Moede, Tilo, Paschen, Meike, Dicker, Andrea, Abdulreda, Midhat H., Åvall, Karin, Ali, Yusuf, Daré, Elisabetta, Köhler, Martin, Ilegems, Erwin, Graham, Mark, Crooke, Rosanne M., Tay, Vanessa Shi Yun, Refai, Essam, Nilsson, Stefan K., Jacob, Stefan, Selander, Lars, Berggren, Per-Olof, Juntti-Berggren, Lisa
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/103306
http://hdl.handle.net/10220/25742
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Institution: Nanyang Technological University
Language: English