Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes
Insulin resistance and β-cell failure are the major defects in type 2 diabetes mellitus. However, the molecular mechanisms linking these two defects remain unknown. Elevated levels of apolipoprotein CIII (apoCIII) are associated not only with insulin resistance but also with cardiovascular disorders...
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Main Authors: | Leibiger, Ingo B., Leibiger, Barbara, Moede, Tilo, Paschen, Meike, Dicker, Andrea, Abdulreda, Midhat H., Åvall, Karin, Ali, Yusuf, Daré, Elisabetta, Köhler, Martin, Ilegems, Erwin, Graham, Mark, Crooke, Rosanne M., Tay, Vanessa Shi Yun, Refai, Essam, Nilsson, Stefan K., Jacob, Stefan, Selander, Lars, Berggren, Per-Olof, Juntti-Berggren, Lisa |
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Other Authors: | Lee Kong Chian School of Medicine (LKCMedicine) |
Format: | Article |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/103306 http://hdl.handle.net/10220/25742 |
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Institution: | Nanyang Technological University |
Language: | English |
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