Human beta cells produce and release serotonin to inhibit glucagon secretion from alpha cells

Human beta cells produce and release serotonin to inhibit glucagon secretion from alpha cells

In the pancreatic islet, serotonin is an autocrine signal increasing beta cell mass during metabolic challenges such as those associated with pregnancy or high-fat diet. It is still unclear whether serotonin is relevant for regular islet physiology and hormone secretion. Here, we show that human bet...

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Bibliographic Details
Main Authors: Almaça, Joana, Molina, Judith, Menegaz, Danusa, Pronin, Alexey N., Tamayo, Alejandro, Slepak, Vladlen, Berggren, Per-Olof, Caicedo, Alejandro
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2018
Subjects:
DRNTU::Science::Medicine
Serotonin
Beta Cell
Online Access:https://hdl.handle.net/10356/89948
http://hdl.handle.net/10220/46464
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/89948
http://hdl.handle.net/10220/46464

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