Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers

• المؤلفون الرئيسيون: Park, Jung Eun, Sun, Yang, Lim, Sai Kiang, Tam, James P., Dekker, Matthijs, Chen, Hong, Sze, Siu Kwan
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Cancer epigenetics; Cancer prevention
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83567; http://hdl.handle.net/10220/42652
• المؤسسة: Nanyang Technological University

Dietary intake of bioactive phytochemicals including the cruciferous vegetable derivative phenethyl isothiocyanate (PEITC) can reduce risk of human cancers, but possible epigenetic mechanisms of these effects are yet unknown. We therefore sought to identify the molecular basis of PEITC-mediated epig...