Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers

• Main Authors: Park, Jung Eun, Sun, Yang, Lim, Sai Kiang, Tam, James P., Dekker, Matthijs, Chen, Hong, Sze, Siu Kwan
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2017
• Subjects: Cancer epigenetics; Cancer prevention
• Online Access: https://hdl.handle.net/10356/83567; http://hdl.handle.net/10220/42652
• Institution: Nanyang Technological University

Dietary intake of bioactive phytochemicals including the cruciferous vegetable derivative phenethyl isothiocyanate (PEITC) can reduce risk of human cancers, but possible epigenetic mechanisms of these effects are yet unknown. We therefore sought to identify the molecular basis of PEITC-mediated epig...