Tissue resident memory T cells in the human conjunctiva and immune signatures in human dry eye disease

• المؤلفون الرئيسيون: Bose, Tanima, Lee, Ryan, Hou, Aihua, Tong, Louis, Chandy, Kanianthara George
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Immunology; Drug discovery
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83599; http://hdl.handle.net/10220/42680
• المؤسسة: Nanyang Technological University

Non-recirculating resident memory (TRM) and recirculating T cells mount vigorous immune responses to both self and foreign antigens in barrier tissues like the skin, lung and gastrointestinal tract. Using impression cytology followed by flow cytometry we identified two TRM subsets and four recircula...