A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue

• Main Authors: Hou, Aihua, Bose, Tanima, Chandy, Kanianthara George, Tong, Louis
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2018
• Subjects: Immunology; Dry Eye Disease
• Online Access: https://hdl.handle.net/10356/88465; http://hdl.handle.net/10220/44618
• Institution: Nanyang Technological University

Dry eye disease is a very common condition that causes morbidity and healthcare burden and decreases the quality of life. There is a need for a suitable dry eye animal model to test novel therapeutics to treat autoimmune dry eye conditions. This protocol describes a chronic autoimmune dry eye rat mo...