Mechanisms of Yersinia YopO kinase substrate specificity

• Main Authors: Lee, Wei Lin, Singaravelu, Pavithra, Wee, Sheena, Xue, Bo, Ang, Khay Chun, Gunaratne, Jayantha, Grimes, Jonathan M., Swaminathan, Kunchithapadam, Robinson, Robert C.
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2017
• 主題: Protein–protein interaction networks; Phosphorylation
• 在線閱讀: https://hdl.handle.net/10356/83602; http://hdl.handle.net/10220/42660

Yersinia bacteria cause a range of human diseases, including yersiniosis, Far East scarlet-like fever and the plague. Yersiniae modulate and evade host immune defences through injection of Yersinia outer proteins (Yops) into phagocytic cells. One of the Yops, YopO (also known as YpkA) obstructs phag...