Mechanisms of Yersinia YopO kinase substrate specificity

• المؤلفون الرئيسيون: Lee, Wei Lin, Singaravelu, Pavithra, Wee, Sheena, Xue, Bo, Ang, Khay Chun, Gunaratne, Jayantha, Grimes, Jonathan M., Swaminathan, Kunchithapadam, Robinson, Robert C.
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2017
• الموضوعات: Protein–protein interaction networks; Phosphorylation
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/83602; http://hdl.handle.net/10220/42660
• المؤسسة: Nanyang Technological University

Yersinia bacteria cause a range of human diseases, including yersiniosis, Far East scarlet-like fever and the plague. Yersiniae modulate and evade host immune defences through injection of Yersinia outer proteins (Yops) into phagocytic cells. One of the Yops, YopO (also known as YpkA) obstructs phag...