Design and Synthesis of Lactams Derived from Mucochloric and Mucobromic Acids as Pseudomonas aeruginosa Quorum Sensing Inhibitors

Bacterial infections, particularly hospital-acquired infections caused by Pseudomonas aeruginosa, have become a global threat with a high mortality rate. Gram-negative bacteria including P. aeruginosa employ N-acyl homoserine lactones (AHLs) as chemical signals to regulate the expression of pathogen...

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Bibliographic Details
Main Authors: Almohaywi, Basmah, Taunk, Aditi, Nizalapur, Shashidhar, Iskander, George, Griffith, Renate, Kumar, Naresh, Wenholz, Daniel S., Biswas, Nripendra N., Ho, Kitty K. K., Rice, Scott A., Black, David StC.
Other Authors: Singapore Centre for Environmental Life Sciences Engineering
Format: Article
Language:English
Published: 2018
Subjects:
Online Access:https://hdl.handle.net/10356/84293
http://hdl.handle.net/10220/45109
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Institution: Nanyang Technological University
Language: English
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