High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine

• Main Authors: Duszka, Kalina, Burcelin, Rémy, Wahli, Walter, Sansonetti, Philippe J., Pédron, Thierry, Tomas, Julie, Mulet, Céline, Saffarian, Azadeh, Cavin, Jean-Baptiste, Ducroc, Robert, Regnault, Béatrice, Tan, Chek Kun
• 其他作者: Lee Kong Chian School of Medicine (LKCMedicine)
• 格式: Article
• 語言: English
• 出版: 2016
• 主題: High-fat diet; Microbiota
• 在線閱讀: https://hdl.handle.net/10356/84359; http://hdl.handle.net/10220/41791

Diet is among the most important factors contributing to intestinal homeostasis, and basic functions performed by the small intestine need to be tightly preserved to maintain health. Little is known about the direct impact of high-fat (HF) diet on small-intestinal mucosal defenses and spatial distri...