Drosophila expressing human SOD1 successfully recapitulates mitochondrial phenotypic features of familial Amyotrophic Lateral Sclerosis

Mitochondrial pathology is a seminal pathogenic hallmark of familial amyotrophic lateral sclerosis (FALS) which is extensively manifested by human patients and mutant SOD1G93A mammalian models. Rodents expressing human FALS-associated mutations successfully mimic several human disease features; alth...

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Bibliographic Details
Main Authors: Gallart-Palau, Xavier, Ng, Chee-Hoe, Ribera, Joan, Sze, Siu Kwan, Lim, Kah-Leong
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/84611
http://hdl.handle.net/10220/41891
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Institution: Nanyang Technological University
Language: English
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