A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides

• Main Authors: Serra, Aida, Hemu, Xinya, Nguyen, Ngan T. K., Sze, Siu Kwan, Tam, James P., Nguyen, Giang Kien Truc
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2016
• Online Access: https://hdl.handle.net/10356/84675; http://hdl.handle.net/10220/41943
• Institution: Nanyang Technological University

Cyclotides are plant cyclic cysteine-rich peptides (CRPs). The cyclic nature is reported to be gene-determined with a precursor containing a cyclization-competent domain which contains an essential C-terminal Asn/Asp (Asx) processing signal recognized by a cyclase. Linear forms of cyclotides are rar...