Structure of the Open Reading Frame 49 Protein Encoded by Kaposi Sarcoma-Associated Herpesvirus

• Main Authors: Hew, Kelly, Veerappan, Saranya, Sim, Daniel, Cornvik, Tobias, Nordlund, Pär, Dahlroth, Sue-Li
• Other Authors: Jung, Jae U.
• Format: Article
• Language: English
• Published: 2017
• Subjects: Herpesvirus; Kaposi's sarcoma-associated herpesvirus
• Online Access: https://hdl.handle.net/10356/84995; http://hdl.handle.net/10220/42068
• Institution: Nanyang Technological University

Herpesviruses alternate between the latent and the lytic life cycle. Switching into the lytic life cycle is important for herpesviral replication and disease pathogenesis. Activation of a transcription factor replication and transcription activator (RTA) has been demonstrated to govern this switch i...