Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa

Since its discovery 22 years ago, the bacterial cell-to-cell communication system, termed quorum sensing (QS), has shown potential as antipathogenic target. Previous studies reported that ajoene from garlic inhibits QS in opportunistic human pathogen Pseudomonas aeruginosa. In this study, screening...

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Main Authors: Fong, July, Yuan, Mingjun, Jakobsen, Tim Holm, Mortensen, Kim T., Delos Santos, May Margarette Salido, Chua, Song Lin, Yang, Liang, Tan, Choon Hong, Givskov, Michael, Nielsen, Thomas Eiland
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2017
Subjects:
Online Access:https://hdl.handle.net/10356/85223
http://hdl.handle.net/10220/43675
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Institution: Nanyang Technological University
Language: English