Collective cell migration on artificial extracellular matrix proteins containing full-length fibronectin domains

• Main Authors: Fong, Eileen., Tirrell, David A.
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2011
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/85262; http://hdl.handle.net/10220/6946
• Institution: Nanyang Technological University

The discovery of the cell-adhesive properties of the Arg-Gly-Asp (RGD) sequence located in the tenth type III domain of fi bronectin triggered widespread use of RGD-functionalized materials for directing cell behavior. [ 1,2 ] In studies of cell adhesion and migration, however, cell responses on...