Identification and characterization of roseltide, a knottin-type neutrophil elastase inhibitor derived from hibiscus sabdariffa

Plant knottins are of therapeutic interest due to their high metabolic stability and inhibitory activity against proteinases involved in human diseases. The only knottin-type proteinase inhibitor against porcine pancreatic elastase was first identified from the squash family in 1989. Here, we report...

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Main Authors: Nguyen, Giang Kien Truc, Tam, James Pingkwan, Loo, Shining, Kam, Antony, Xiao, Tianshu, Liu, Chuan Fa
其他作者: School of Biological Sciences
格式: Article
語言:English
出版: 2018
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在線閱讀:https://hdl.handle.net/10356/85406
http://hdl.handle.net/10220/46681
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機構: Nanyang Technological University
語言: English